.
Discovery Experimental & Development Inc. (DEDI)
This website was written by:
James Kimball
Please Select A Category
Selegiline Hydrochloride Research
Prior and while Discovery Experimental and Development, Inc. (DEDI) was developing LDC; DEDI and its associates were reviewing the hundreds of trial results in Europe using the chemical Selegiline Hydrochloride or similar.
Not all the trials in Europe reflected their alleged Selegiline HCL products, or similar were always effective or consistent. The trial results revealed enough information to suggest that if a Selegiline HCL product, or similar were developed to perfection, the results might be astounding.
The trial results of the products produced in Europe revealed those products to be sporadically effective in: Parkinson's Disease, Alzheimer's Disease, tremors, dementia, senility, cognitive functions, mobility and pain relief in people. While one late trial result revealed a dramatic increase in life extension in rats.
It was concluded that if a properly made Selegiline HCL product, or similar were to be developed, it would not produce sporadic results and could very well produce better results while addressing more afflictions than had already been revealed in European trials.
The way a properly made Deprenyl product should work was revealed by the Europeans. A properly made Deprenyl product should pass through the blood brainbarrier easily and come to rest on a tissue in the brain called the Substantia Nigra.
Very few products will pass through the blood brain barrier. This barrier is the body's natural defense mechanism to stop foreign objects from getting into the brain, damaging brain cells and killing us.
However, for a Deprenyl product to work it needed to pass easily through the body's natural barrier, so it could reach the brain and stimulate the Substantia Nigra tissue.
The Substantia Nigra is a tissue in the brain which produces a chemical within the brain. The scientists have named the chemical produced by this Substantia Nigra tissue, dopamine.
This chemical called dopamine is one of our body's majorlife links. Without the Substantia Nigra tissue producing dopamine, it is concluded we would not live past the age of 5 years old. However, it is a hypothesized that if a product were developed that could cause the Substantia Nigra to continue to produce dopamine, the life expectancy in humans could be increased 50% or higher.
DEDI's Liquid Deprenyl Citrate
This is exactly what happened with the rats that received DEDI's properly made Deprenyl product.
The shortest living rat, receiving DEDI's LDC, lived about 10% longer than the longest living rat that did not receive the product. However, the longest living rats receiving DEDI's properly made Deprenyl lived almost 80% longer than the longest living rat that did not receive Liquid Deprenyl Citrate at all.
The rat study absolutely proved that DEDI's properly made Deprenyl product had the potential not only to address a multitude of serious life-threatening and debilitating diseases, it had the distinct possibility of increasing the life of humans by 50% or more.
The Substantia Nigra tissue degenerates as we get older and produces less and less dopamine. The chemical dopamine keeps the brain cells protected from attackers which destroybrain cells. Scientists have named some of these attackers Monoamine Oxidize. Dopamine is a Monoamine Oxidize inhibitor, and stops the Monoamine Oxidizers from attacking, immobilizing, and killing brain cells.
As we age, and the Substantia Nigra degenerates, this tissue produces less dopamine to protect brain cells. The Monoamine Oxidize then starts its lethal attack against brain cells. As the brain cells are being attacked, people become immobile, suffer from dementia, and senility, memory and speech problems occur and so on.
If for some reason the Substantia Nigra degenerates too quickly or something goes wrong with that tissue, the dopamine content drops off faster than normal and these people suffer from terminal disease called "Parkinson's Disease".
One of the actions of a properly developed and manufactured Deprenyl product is, once it gets into the brain, it stimulates the Substantia Nigra tissue to produce more dopamine. With the dopamine content coming back to normal, the Parkinson's symptoms appeared to improve in the European trials.
DEDI's 99% Pure Liquid Selegiline
When DEDI first developed their LDC; their liquid Selegiline, the purity level, was at 99% pure. The purity level was increased shortly thereafter to 99.9903% using a sophisticated purifying procedure developed by Dr. Owen. Dr. Owen had decided upon another product; citric acid to use as one of the stabilizing agents in LDC. Citric acid is another one of the few chemicals which will pass through the blood brain barrier easily.
In essence what Dr. Owen and his team had developed was a brand new product, which was all natural, with 2 of its ingredients passing through the blood brain barrier easily, to accomplish their task.
Once DEDI was aware that citric acid passes easily through the blood brain barrier, DEDI did what the FDA should have done over 50 years ago.
The Over-Looked Severe Warning
Kimball contacted one of the foreign research teams DEDI was working with, at the University of Toronto. Because orange juice contains citric acid, DEDI wanted to know two things. If a person were to take any medication with 4 - 8 oz glass of orange juice, would the medication the person was taking, get into the brain? And if so, how long should a person wait after drinking a 4 - 8 oz glass of orange juice, before taking medication, or dietary supplement, so those products will not get into the brain.
The research team got back with Kimball and advised him, that most any medication or dietary supplement taken with orange juice, would in fact get into the brain, using citric acid as its carrier. They advised Kimball if a person took medication or dietary supplements 1/2 an hour prior, or 1/2 hour after drinking orange juice, the substance in general should not get through the blood brain barrier.
As soon as that information was received, DEDI sent out a notice to all its customers advising them not to take any medication, or dietary supplements within 30 minutes of drinking orange juice due to the fact those substances could penetrate the blood brain barrier and cause adverse side effects. DEDI advised them to check with their physician before taking any medication, or supplement with orange juice.
Additionally DEDI put on the labels of its products DO NOT take this product or any other product within 30 minutes of drinking orange juice or ingesting any substance containing citric acid. DEDI received hundreds of calls from doctors asking why. When they were explained why, the doctors agreed.